One significant Black-led labor strike in American history is the Brotherhood of Sleeping Car Porters Strike of 1925. The Brotherhood of Sleeping Car Porters was the first African American labor union to receive a charter in the United States. The union was formed in 1925 by A. Philip Randolph, a prominent civil rights leader, to represent and advocate for the rights of African American workers employed as porters on the Pullman Company's luxury trains.

The porters faced discrimination, long hours, low pay, and poor working conditions. Despite these challenges, the Brotherhood of Sleeping Car Porters grew in numbers and strength. In 1925, the union initiated a strike against the Pullman Company to demand better wages, fair working conditions, and an end to racial discrimination.

The strike lasted for several years, with the porters facing intimidation, threats, and violence from both the company and local authorities. However, the union persevered, and in 1937, the Pullman Company finally signed a historic agreement with the Brotherhood of Sleeping Car Porters, granting the porters improved wages and working conditions.

The Brotherhood of Sleeping Car Porters Strike was a pivotal moment in the history of labor and civil rights, as it not only improved the lives of African American workers but also demonstrated the power of collective action and solidarity in the face of injustice.